TL;DR:
- People with medullary thyroid cancer, Multiple Endocrine Neoplasia type 2, pancreatic conditions, gut issues like gastroparesis, kidney disease, gallstone history, and allergies should avoid GLP-1 drugs. Pregnant / breastfeeding / planning for pregnancy also need to avoid them.
- Common side effects include nausea, diarrhea, vomiting, headaches, dizziness, mood changes, and injection site reaction.
- GLP-1 drugs require lifestyle changes, have risks associated with long-term usage, and may lead to rapid weight regain once stopped.
- Bariatric surgery offers better long-term weight loss, fewer side effects, and better nutritional balance.
- GLP-1 drugs including Ozempic, Wegovy, Mounjaro, Trulicity, Victoza, and Saxenda have different focuses and dosages. However, they can lead to long-term health issues like pancreas, gallbladder, and thyroid damage, gut issues, and potential heart problems.
- It's crucial to consider various options and consult with professionals before starting a GLP-1 regimen or surgery.
Not every treatment is right for everyone, especially with drugs like GLP-1 receptor agonists. As a surgeon at Nevada Surgical, I believe it's crucial to know who should steer clear of these medications. Certain medical conditions make GLP-1 drugs a risky choice. In this article, discover who should avoid these drugs, understand the side effects, and uncover the potential complications. Stay informed for your well-being.
Who Should Avoid GLP-1 Drugs Due to Medical Conditions?
Who Is Not a Candidate for GLP-1?
Certain health issues mean these drugs are not safe.
Thyroid Cancer Risk:
People with medullary thyroid cancer should not take GLP-1 drugs. The risk is too high. Those with Multiple Endocrine Neoplasia type 2 (MEN 2) also need to avoid them.
Who Should Avoid Ozempic?
People with pancreas issues should skip Ozempic. It might worsen conditions like pancreatitis. These drugs impact the pancreas and could lead to other problems.
Are Gut Issues a Problem for GLP-1 Users?
Yes, if you have gastro issues like gastroparesis, these drugs can make it worse. GLP-1 drugs slow down the stomach. This can lead to more nausea or constipation.
Kidney Disease Is a Big Flag
These drugs can lead to fluid loss and affect kidneys badly. This is worse for older adults or those on many drugs. Consult your kidney doctor first.
Let’s Talk About the Gallbladder
GLP-1 drugs can cause gallstones. If you've had gallbladder issues, these drugs might not be safe. Surgery to remove the gallbladder may help.
Pregnant or Breastfeeding? Walk Away from GLP-1s
These drugs aren't well-tested in pregnant people or babies. The risk is not worth it. Avoid them if you're pregnant or planning to be.
What if You Are Allergic?
Do not take GLP-1 drugs if you're allergic. Rash or swelling indicates you should stop. Consider food plans, surgery, or lifestyle changes instead.
The Big Picture
Many who struggle with GLP-1 drugs find success with bariatric surgery. Surgery offers reliable and safer outcomes. It manages weight without the side effects associated with GLP-1 drugs.
What Are the Short-Term and Common Side Effects of GLP-1 Drugs?
What Happens When You Start GLP-1?
You may feel sick to your stomach at first. These drugs slow stomach emptying and reduce appetite. This can lead to weight loss but with some short-term issues.
Can GLP Cause Diarrhea?
Yes, diarrhea often occurs. This happens because your gut adjusts. It might last for weeks. Manage it by staying hydrated and eating simple foods.
Vomiting and Other Side Effects
Some people feel queasy or vomit. Small, soft meals can help. Headaches and dizziness happen too. They are due to fewer calories in your system.
Mood Shifts and Injection Site Reaction
Mood changes include feeling tired or sad. Eating enough helps. Red bumps from shots are normal, but swelling is not. Consult a doctor if symptoms persist.
Comparing Surgery and GLP-1 Drugs
Bariatric surgery surpasses GLP-1 drugs in delivering long-term weight loss. It doesn't come with gut or energy issues. Surgery gives more stable and lasting results.
Who Should Be Cautious About GLP-1 Drugs for Weight Loss?
With a BMI under 27 and no health issues, avoid GLP-1 drugs. They can lead to poor nutrition. They require lifestyle changes to work well. Exiting them can lead to quick weight gain.
Which GLP-1 Is Best for Weight Loss?
Wegovy causes the most weight loss, but it requires long-term lifestyle changes. Ozempic and Mounjaro can help with weight but focus on diabetes.
Teens and Older Adults
Teens and older adults need more caution. GLP-1 drugs can affect growth and present other risks. Bariatric surgery, supervised carefully, offers a safer option.
Eating Disorders and Fast Weight Loss
Avoid GLP-1 drugs if you've had an eating disorder. They can trigger harmful habits. They cause muscle loss, unlike surgery, which aims to protect muscle.
Professional Guidance Is Necessary
Doctors should guide treatment. GLP-1 drugs don't train you for better habits. Surgery involves a full team to ensure long-term success.
Long-Term Complications of GLP-1 Drugs
Long-Term Side Effects
Continued use of GLP-1 drugs can harm your pancreas, gallbladder, thyroid, and gut.
The Pancreas and Gallbladder
These drugs increase the risk of pancreatitis and gallstones. They can lead to severe health issues over time.
Thyroid Tumors and Gut Health
Animals tests link GLP-1 drugs to tumors. They also cause long-term gut issues. Gastroparesis may result from their constant use.
Nutrition and Heart Health
Long-term use could lead to vitamin loss and potential heart issues. Surgery provides a better balance and nutritional guidance.
No Long-Term Study
Studies rarely extend beyond a few years. Bariatric surgery has better-documented long-term effects and reduces heart risks.
GLP-1 Drug Options and Effects
Available Drugs
The list includes Ozempic, Wegovy, Mounjaro, Trulicity, Victoza, and Saxenda. They help with insulin and hunger, but surgeries offer long-term solutions.
Drug Differences
Each drug suits different needs. Wegovy and Saxenda focus on weight. Mounjaro combines functions. Daily or weekly dosages vary.
The Big Part Not to Skip
These drugs often lead to short-term results. With surgery, weight stays off and dependency on drugs reduces. Surgery often leads to reversing type 2 diabetes too.
Conclusion
GLP-1 drugs may help some, but they're not for everyone. Consider whether bariatric surgery could offer better, safer results. Talk to a trusted advisor and look beyond the short-term benefits.
Conclusion
We've explored who should avoid GLP-1 drugs and looked closely at their side effects. Some people may face issues due to medical conditions like thyroid cancer or severe gastrointestinal diseases. Common side effects include nausea and diarrhea, and some may see changes in mood or energy. While GLP-1 drugs can aid in weight loss, they aren't suitable for everyone, like those with certain medical histories or who need proper clinical evaluation. Long-term effects can impact organs like the pancreas, and ongoing research is key. Consider both their risks and benefits, and consult with a healthcare provider for personalized advice.
If you're considering weight loss options and are concerned about the potential risks of GLP-1 drugs, bariatric surgery may offer a safer and more effective solution. At Nevada Surgical, our experienced team is ready to guide you through this life-changing journey, ensuring you achieve lasting results without the health risks associated with certain medications. Learn more about how our tailored surgical options can help you achieve a healthier future. Contact us today for a consultation!